Regenerative Medicine: Learn More About Adipose-Derived Regenerative Cells and PRP

Regenerative medicine can be very effective when coupled with chiropractic and physical therapy. At The Center for Manual Medicine and Regenerative Orthopedics, we combine Adipose-Derived Regenerative Cells and PRP (Platelet-Rich Plasma) to help our patients recover quickly. Here’s how these treatments work:

What Are Adipose-Derived Regenerative Cells (ADRCs)

The human body is composed of tissues and organs that are formed by specialized groups of cells. There are trillions of cells in your body, and the vast majority are assigned to specific tasks, just like employees from different departments in the same company. However, Adipose-Derived Regenerative Cells are special because they can adapt to the roles of various cell types. They’re just like professionals who wear many hats.   

What is PRP?

PRP stands for Platelet-Rich Plasma, which is a medical treatment that utilizes your blood to heal damaged tissues and organs. Platelets are a sticky component of your blood that adhere to damaged blood vessels to stop bleeding. PRP is mostly used to treat elbow, wrist, hand, knee, ankle, foot, shoulder, back, and hip injuries.

What Is the Procedure?

For Adipose-Derived Regenerative Cells, we use local anesthesia to numb the skin and make a very small incision.  Then we use a special cannula to collect tissue from your fat, or bone marrow.  While the procedure doesn’t hurt in most cases, you might feel a small amount of discomfort.   We then Ultrasound guide the ADRC’s into the source of your pain.  For PRP, we collect your blood, extract the Platelet Rich Plasma, and ultrasound guide it into the painful area.

Doug Frye, MD has created the most in-depth Adipose-Derived Regenerative Cell protocol in the Midwest.  At The Center For Regenerative Orthopedics, we set our patients up for success! All of our patients receive an in-depth hands-on evaluation and Ultrasound Diagnosis by the only certified Musculoskeletal Ultrasounds Sonographer in the region. Dr. Frye utilizes a 3-step process, that entails 3 injections instead of 1. The Fellowship trained Physical Therapists to work closely with Dr. Frye to ensure that the patient receives the best possible Physical Therapy for their specific case and everyone that receives ADRCs is put into a 2-year follow-up.


You’ll have a follow-up exam scheduled two weeks after the procedure. It’s normal to experience a few symptoms in the first few days, such as pain and swelling. We encourage our patients to talk to us if they have further questions, and before taking any medications. Once you start recovering, you’ll be ready to begin physical therapy.

At The Center for Manual Medicine and Regenerative Orthopedics, we combine regenerative medicine, chiropractic, and physical therapy to help our patients relieve pain and restore motion. Contact us through our website or call us at (785) 271-8100 to book an appointment.